| ORIGINAL ARTICLE |
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| Year : 2016 | Volume
: 4
| Issue : 2 | Page : 89-92 |
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Chemical study on the effect of Shodhana on Toxic Principle of Gunja Beeja
Nilima N Wadnerwar1, Shriramji Jyotishi2, Ulhas Duragkar3
1 Assistant Professor, Department of Agadtantra, MGACHRC, salod (H), Wardha (M.S.), India
2 Professor, Research Methodology, MGACHRC, Salod(H), Wardha, India
3 (Retired) Professor, Department of Agadtantra, Shri Ayurved College, Nagpur, India
Correspondence Address:
Nilima N Wadnerwar
Assistant Professor, Department of Agadtantra, MGACHRC, salod (H), Wardha (M.S.)
India
 Source of Support: None, Conflict of Interest: None
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Inspite of harmful and dangerous effects, poisons are used therapeutically as medicine after shodhana procedure. Shodhana Samskara (process of purification) affects the morphological as well as active part of the crude drug. As these processes are being used since very long time, it becomes necessary to study these changes systematically and scientifically with the help of modern methods, so as to give a scientific base to these processes especially when the drug is toxic. The Shodhan procedure not only purifies the drug but also minimizes its untoward effects. This type of toxicity has been evaluated with the help of pharmaceutical and analytical study of Gunja (Abrusprecatorius) to study purification process systematically and scientifically. In this study, after shodhana of both the varieties of Gunja beeja by Dolayantra using three different media, physico-chemical analysis was done. Colour of all the six samples after shodhana has changed. Reduction of values was observed in weight of samples treated with Kanji and distilled water. Total ash value, acid insoluble ash values & alcohol extract values reduced in all the purified samples. Aqueous extract value of Rakta and Shwet Gunja samples purified by Godugdha are more than the raw samples. pH value after detoxification process revealed some increase though the nature of the solution remained acidic. Conductivity of the solutions of sample treated with distilled water and Kanji, found to be reduced. Thus the study has provided positive effects of Shodhan Samskara to avoid the hazardous effects of the toxic principle.
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