| ORIGINAL ARTICLE |
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| Year : 2020 | Volume
: 8
| Issue : 3 | Page : 193-199 |
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Pharmaceutico analytical profile of Kushmanda Avaleha and its modified dosage form as Kushmanda granules
Neha S Chavhan1, Bharat J Rathi1, Dhananjay D Deshmukh2
1 Department of Rasashastra and Bhaishajya Kalpana, Mahatma Gandhi Ayurveda College, Hospital and Research Centre (MGACH & RC), Wardha, Maharashtra, India
2 Department of Shalya Tantra, Mahatma Gandhi Ayurveda College, Hospital and Research Centre (MGACH & RC), Wardha, Maharashtra, India
Correspondence Address:
Dr. Neha S Chavhan
Deparment of Rasashastra and Bhaishajya Kalpana, Mahatma Gandhi Ayurveda College Hospital and Research Centre, Wardha 442001, Maharashtra
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/JISM.JISM_36_20
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Background: Kushmanda Avaleha (KA, confection) has been described in Sharangdhar Samhita as a drug of choice in Raktapitta Chikitsa (hemorrhage). Ayurveda mentioned Five Basic Kalpanas, which are called Panchvidha Kashya Kalpana. Panchvidha Kashya Kalpana has several drawbacks, such as less palatability, shorter shelf life, etc. Hence, to overcome these drawbacks, secondary formulations were developed. Avaleha Kalpana was a secondary formulation developed by using primary formulations, such as Swaras (juice), Kwatha (decoctions), etc. Avaleha formulation was prepared by using herbal medicinal drugs and food articles such as sugar, ghee (clarified butter), honey etc. Administering proper dose of Avaleha is difficult in new era than Avaleha convert into granules form because, considering the changing scenario of the society, converting traditional dosage forms into more palatable, easily absorbable forms without changing desired therapeutic effects becomes need of the hour. In the current study, an attempt has been made to convert KA into granules form, which is the first step toward research on the formulation; hence, the current work was planned. Aim: Analytical study of KA and its modified dosage form as Kushmanda granules (KG)Materials and Methods: Three batches of KA were prepared as per the reference of Sharangdhar Samhita (8/22–28), and the same is converted into granules by adopting standard operative procedures. Result and Conclusion: Loss on drying at 105°C, total ash, acid-insoluble ash, alcohol-soluble extractives, water-soluble extractives, pH, total sugar, reducing sugar, nonreducing sugar, and total fat and moisture content in the range of Avaleha is 2.3%, 0.7%, 0.103%, 71.22%, 77.12%, 4.2%, 78.15%, 68.21%, 5.6%, and 2.92%. The range of granules is 3.1%, 1.2%, 0.36%, 38.09%, 41.2%, 3.53, 80.17, 78.12, 4.5, 0.92, and 3.12, respectively. |
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