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Year : 2020  |  Volume : 8  |  Issue : 4  |  Page : 304-307

Shelf-life evaluation of Marichyadi Lepa prepared with Agnipaki and Bhanupaki method: A preliminary assessment

1 Department of RS & BK, B.G.Garaiya Ayurveda College, Rajkot, India
2 Department of Rasa Shastra and Bhaishajya Kalpana Including Drug Research, IPGT & RA, Jamnagar, India
3 Department of RS & BK, All India Institute of Ayurveda, New Delhi, India

Correspondence Address:
Dr. Sandhya Barad
Department of RS & BK, B.G.Garaiya Ayurveda College, Rajkot, Gujarat.
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JISM.JISM_104_20

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Introduction: The shelf life of a drug can be considered up to the period when it gets deteriorated and it does not experience any alteration in its physicochemical state. Every product has a shelf life, which depends on various physical, chemical, environmental, and biological factors. Ancient seers have clarified the shelf life of various compound formulations. However, there is a need to revalidate and ascertain the shelf life of individual formulations by following parameters that are prevalent in the respective scenario. Aim: To evaluate the shelf life of Marichyadi Lepa prepared by Agnipaki (heating by using fire) method (MLA) and Bhanupaki (heating by using sunlight) method (MLB) through an accelerated stability study. Subjects and Methods: Physicochemical parameters were measured at 40 ± 2°C temperature and 75 ± 5% relative humidity. Analysis was repeated at intervals of 1, 3, and 6 months, and average 10% degradation of both the test drug samples was calculated and extrapolated to find the shelf life. Results: MLB and MLA showed a shelf life of 6.24 months and 5.50 months, respectively. Conclusion: MLB is comparatively more stable than the sample prepared with MLA.

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