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July-September 2018 Volume 6 | Issue 3
Page Nos. 96-174
Online since Tuesday, September 10, 2019
Accessed 8,383 times.
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EDITORIAL |
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Need and scope of pharmacokinetic evaluation of Ayurveda medicines |
p. 96 |
Dhirajsingh Rajput
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ORIGINAL ARTICLES |
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Comparative analytical evaluation of Naga Bhasma prepared by two different methods |
p. 100 |
Dhirajsingh Rajput, BJ Patgiri, R Galib, PK Prajapati
Introduction: The difference in the analytical profile of Bhasma prepared by different method is different and thus such analytical works may gives probable logics differentiating the therapeutic actions. Therefore present work was planned for analytically evaluation of Naga Bhasma prepared by two different methods.
Material and methods: Naga Bhasma was prepared by using Parada and Gandhaka (sulfur) [NBP] media, another Naga Bhasma was prepared by using Vasa as herbal media (NBH). NBP and NBH were first tested for fulfilling classical criteria of Bhasma, then both batches were analytically evaluated by using modern physico- chemical parameters.
Observation and results: Obtained values of Total Ash, Acid insoluble ash, Loss on drying and Free Sulfur in NBP and NBH are 98.85, 97.67; 79.47, 5.78; 0.07, 0.16 and 22.83, Nil respectively. FTIR study showed presence of organic legends and large number of functional groups in both samples. Higher proportion of Pb, Fe and Cu is detected inNBPthanNBH. Both samples possesses nano-particle size, however NBH is finerthanNBP.
Conclusions: Method of processing significantly affects the physico-chemical properties of Bhasma as all parameters showed major differences in obtained values. Thus based on these findings there is need to consider Bhasma preparative method in Ayurveda formulations as well as while describing it on labels of formulations.
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Analytical standardization of Vidangadi Loha- an Ayurveda formulation |
p. 115 |
Nilesh Temkar, Bharat Rathi, Anita Wanjari, Dhirajsingh Rajput
Vidangadi Lauha is an Ayurveda medicine available in tablet form which is widely utilized. This formulation contain 8 drugs viz. Vidanga (Emblica ribs Burm f.) Haritaki (Terminalia chebula) Bibhitaki (Terminalia belerica) Amalaki (Emblica officinalis) Pippali (Piper longum) Sunthi (Zingiber officinalis)Maricha (Piper nigrum)Louha Bhasma (calcinated Iron) and Guda (jaggery). The analytical standards for this formulation are not available hence present work was planned to establish its analytical standards. Vidangadi Loha was prepared as per reference of Rasendrasara Samgraha. Analytical parameters such as Loss on drying at 105°C, Total Ash value, Acid insoluble ash, Water soluble extractive, Alcohol soluble extractive, pH, Hardness, Dissolution time, Disintegration time, Friability and Reducing sugar were studied. It is observed that reducing sugar (34%) and loss on drying (9.0%) are higher in this formulation while all other parameters are within normal limit. HPLC analysis revealed that Vidangadi Lauha prepared contains multiple phyto-chemicals such as polyphenols, moderately polar compounds, flavonoids/glycosides, antioxidants and very less amount of acid-base components including alkaloids.
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Comparative study on the effect of Siravyadhana and Jalaukavacharana along with Trishothadi Lepam on foot ulcers |
p. 122 |
Reena Jaiswal (Devyani Dasar)
Background: An ulcer is abreak in the continuity of the covering epithelium, either skin or mucous membrane due to molecular death. Usually progressive infection, non-debridement and continuous anti-gravitational stasis does have bad impact in the management of foot ulcers. Aim: A long term multidisciplinary care and integration of traditional new wound healing technologies are required for healthy healing. Materials and Methods: Siravyadhana (vein-puncture) and Jalaukavacharana (Leech application) procedures with Trishothadi Lepamwere used in the present study. Results: Jalaukavacharana has shown better results in wound healing process than Siravyadhana having cumulative 91.66% and 71.60% respectively. Conclusion: The process of Jalaukavacharana was effective for relieving vascular stasis, reducing venous congestion and beginning of revascularization and other wound healing process than Siravyadhana throughout the study.
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Evaluation of third year BAMS students perception and feedback on Teaching- Learning Methods of Kaumarbhritya |
p. 130 |
Renu B Rathi, Bharat Rathi
Introduction: Teaching is a means of offering a unique, definite, and essential social service through specialized training. Kaumarabhritya is Ayurveda Pediatrics which mainly deals with the prevention and treatment of various disorders since conception to adolescent age-group. There are several strategies adopted for encouraging student’s involvement in the learning process of this subject. Objectives: To obtain the perception and feedback of third year BAMS students on teaching-learning methods of Kaumarabhritya. Material and Methods: This was a prospective observational study based on questionnaire, IEC approved educational research project. Questionnaire consisted of total thirty questions under eight heads, including five open ended questions to seek their suggestions on different aspects ofteaching- learning methods. Results: 89.65% students agreed that didactic lecture is mosteffective as compared to othermethods such as integrated teaching; problem based learning, tutorial or group discussion. 99.99% were in view of effective mode with animated or audio-visual lectures as compared to black-board teaching. 79.31% students opined more clinical teaching hours to be allotted as compared to theory with demonstration of signs and examination on patients for better understanding of diseases. Regarding format of question paper and its solving ability, students felt MCQ, BAQ and SAQ then level one type long answer questions (LAQ) easy to solve. Conclusion: Students approved ease and interest in objective structured clinical exam (OSCE) in comparison with traditional practical method and bed side viva-voce. They have been demanding two papers of the subject Kaumarabhritya/Balrog than single paper with shift in final year from third year due to lack of clinical exposure, difficultto understand and less scoring.
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Comparative clinical study of pushkarmula Churna and Pippali Churna in the management of Kaphaj Kasa in children |
p. 138 |
Arun Wankhede, Sushama Khirodkar, Sanjay Gadhe
Children between aged1 to 16 years, the prevalence rate of cough is about 2.05%, which is seen in all over the world. Etiology of cough has broad-spectrum, which ranges from infection to allergens. According to Doshas involve in it, Kasa Roga classified into various types among which Kaphaj Kasa is one of the common problem frequently observed in pediatric practice. Kaphaj Kasa is characterized by the productive cough, dense sputum, heaviness, nasal discharge, loss of appetite and chest pain. Kapha is the dominating Dosha in Balyavastha and is the main culprit in production of Kasa so the incidence is more in pediatric age group. For Shamana the line of treatment that includes oral administration of medicine is of most importance as the administration is very easy and also effective compared to Shodhana in children. Pushkarmula Churna and Pippali Churna mentioned in Yogratnakar and Sarngadhar Samhita respectively. Results of Pippali Churna are more effective in reducing Disturbance of sleep, Sputum and Crepitation than Pushkarmula Churna.
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Effect of Aragwadha (Cassia fistula Linn.) Granules onVibandh (Constipation) |
p. 143 |
Vinod Ade, Bharat Rathi, Dhirajsingh Rajput, Pramod Khobragade
Constipation is a common problem in elderly persons, with its prevalence ranging from 15% to 20% in the community-dwelling elderly population and up to 50% in some studies of nursing home residents. In these patients, constipation results from a combination of risk factors, such as reduced fiber and fluid intake, decreased physical activity resulting from chronic diseases and multiple medications. Ayurveda has clearly mentioned constipation under the heading “ Vibandha” and many herbal drugs have also been described for its management. Aragvadha(Cassia fistula Linn.) is one of the drug frequently used for the treatment of constipation. However detail action of Aragvadhaon various symptoms of constipation in its modified dosage form as granules is not evaluated. Therefore present work was planned.
Aim: To study the efficacy of Aragvadh granules in the management of Vibandha (constipation). Method: 31selected patients of Vibandh were treated by giving Aragwadha granules 5 gm, twice a day before meal. Follow-up was done at 7th, 15th and 30th day. Modified ROME-III questionnaire was utilized to access the effect of therapy. The questionnaire was filled before starting treatment and after completion of treatment. Result: Results were statistically analyzed by paired t test. Statistically significant result observed in 14 studied parameters (p value = 0.043* to = <0.001*) while 3 parameters from the questionnaire showed relief but they were not statistically significant.
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CASE REPORTS |
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Management of Ubhaya Gulfasandhi Shool (unexplained chronic pain of both ankle joints) by Gud Sunthi Yoga |
p. 150 |
Bharat Chouragade, Namrata Chouragade
Pain is often a major symptom in many medical conditions and is one of the most sited reasons for seeking medical assistance. Pain may occur anywhere in the body especially in old age but is very problematic when occurs at young adult age especially in females. Present study is an interesting case of Short stature, Female aged 38 years suffering from shoola (pain) in both Gulfasandhi (ankle joints) since five years. She had bad Prasuti (obstetric) history with three Garbhapatan (abortions) and many complications thereof. She had severe pain in both ankle joints with some Shotha (minimal oedema) with off and on character. The pain was continuous and was not responding to any treatment, steroids, NSAID’S. X-rays and other investigations were not revealing any conspicuous abnormality. She could not do her routine work as well as was unable to stand for more than half an hour. Walking was also sometimes very difficult for her. She had done blood test several times as suggested to her by different physicians from time to time. Her CBC was within normal limits, serum Uric acid level was 6mg/dl, ESR was 29mm, PS was within normal limits, FBS-98, PPBS-131, Thyroid profile was within normal limits, RA factor was negative, CRP was within normal limits, Liver function and KFT was also within normal limits, even lipid profile was normal. Her resting ECG was within normal limits. Her vitals were stable. She was suggested Guda- Sunthi Yoga empty stomach thrice a day in a dose of 2g Sunthi with 5g of Jaggery with lukewarm water. She was counselled for Diet modification, little exercise of joints (passive exercise). After a week she got 20% relief in the pain. She was asked to continue the same for Fifteen days where she got 60% pain reduction and after 12 weeks her pain was completely relived.
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Management of Obsessive Compulsive Disorder (OSD) Through Ayurveda |
p. 157 |
Gaurav Sawarka, Punam Sawarkar
Introduction: Obsessive compulsive disorder (OCD) is a co-morbid condition of psychiatric disorders such as anxiety and depression. It is characterized by obsessions of contamination, followed by washing or accompanied by compulsive avoidance of the presumably contaminated object or Obsession of doubt, followed by a Compulsion of Checking and intrusive obsession of thoughts without a compulsion. There is a vast array of Ayurveda which can potentially add value in management of such type Manas Vikara. OCD can be compared to Atattvabhinevesh and various types of Unmada as described in Ayurveda texts. Panchakarama treatment is great boon to Ayurveda. By collaborative use of Vamana, Shamana treatment and Sattvavajaya Chikitsa showed encouraging results in case study of OCD. Aim: To study efficacy of Panchkarma treatment in the management of OCD. Material and method: 26 years old female patient with history of recurrent washing and cleaning her hands, unexplained fear, insomnia and depression attended the OPD. Vamana with Madanphala decoction was administered, prior to that oleation with Cow ghee was given. After following diet regime, palliative treatment started with Shirodhara and Nasya treatment, Spiritual therapy like Omkar recitation by using basic principles to break pathophysiology of OCD.
Observation and result: The patient got relief in unexplained fear with appreciable recovery in Insomnia, decreased habit of recurrent washing hands and Depression.
Conclusion: Conservative management with Ayurveda principle provides significant relief in unexplained fear and anxiety, feeling of apprehension and fear, Insomnia, worry and. Feeling of uncertainty, anorexia, weight loss and improvement in quality of life of patient.
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SURVEY STUDY |
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Study of knowledge & awareness of HIV/ AIDS among youth in Wadad village of Wardha district |
p. 166 |
Jagruti N Chaple, Aishawarya Rahate
There has been a rapid and uncontrolled expansion of HIV in the developing countries during the last two decades. HIV has became highest rate of spread in the world and it is one of the community health problem in India. Many features contribute to India’s vulnerability concerning the transmission of HIV. One of contributory factor to the rapid spread of the HIV epidemic is lack of adequate knowledge about the disease among the people. The study aimed to understand the knowledge and awareness of rural youth people regarding HIV/AIDS in Wadad Village of Wardha district, Maharashtra.
Objective: To study the knowledge and awareness of HIV/AIDS in the villagers of Wadad. Material & method: A community based cross sectional study was conducted among age group of 15 -35years in village Wadad of Wardha District. Data for this survey was collected by house to house visit using a structured questionnaire through interviewing and observation during Community Health Care Program from Mahatma Gandhi Ayurveda Medical College Hospital and Research Centre (DMIMS).
Result: Total 150 subjects participated in the study ,99 were male and 51 were female subjects, 62 % subjects were found to have knowledge about HIV/AIDS. 81.72% people having some knowledge of HIV said that it is preventable. While 72.04% people said that it is non curable disease.
Conclusion: Literacy and media exposure are factors that determine awareness of HIV among them and can be helpful to raise their knowledge regarding HIV/AIDS. It is concluded that 62% people have information about HIV/AIDS.
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CONFERENCE PROCEEDING REPORTS |
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“6 Days CME (RoTP) for Teachers of Agadtantra” |
p. 170 |
Sonali Chalakh |
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“Piyush - 2018” World Breastfeeding Week Celebration |
p. 172 |
Priyanka Shelotakar
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