Agadtantra is sixth branch of Ashtang Ayurveda which deals with management of animate & inanimate poisoning. Due to enhancement in technology the environment is polluted & hence we come across more toxic substances which interfere with the living creature of the world .The present study is an attempt to evaluate & establish the ancient modality of the treatment on modern methods. On detail study & after comparison it was found that these 24 modalities of treatment are complete in terms of treatment of poisoning. As on day it was interesting to note that no new avenues has been added to principles of treatment except advancement in new equipments, methodology & investigation.

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Sthoulya (Obesity) is an increasing and worrisome problem in present population of age group 20-40 years as its complications are contributing to hazardous diseases like diabetes, heart disorders, etc. The reason behind this is altered life style of the population. Those who want to reduce the weight, find it difficult as the exercises, gym practices and dietary restrictions are difficult to follow regularly. Ayurveda has described Sthoulya in “Ashta Ninditiya” (eight unappreciated) conditions as Ati Sthoolata is not a symptom of Swasthya. Further, to overcome this condition, Ayurveda has mentioned various treatment modalities like Vaman (Vomiting), Virechan (Purgation), Vasti (Enema), Abhyang (Massage), Swedan (Fomentation), Udvartana (Rubbing), Yogasanas (Postural exercises), Pranayam (Breathing exercises), dietary regimen etc. trying to perform Apunarbhava Chikitsa (Treatment without complications) according to the Prakriti (Constitution) of the patient. When Shigru Taila Lekhan Vasti was given to a patient of Sthoulya, his weight was reduced by 4.5kg in 45 days without any exercise and dieting. This case study explains the role of Shigru Tail Vasti in Sthoulya.

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Psoriasis is one of the commonest non infective inflammatory skin disease characterized by raised silvery scaly lesions. Lesions most commonly are seen on elbow, knee and lower back. In Ayurveda this disorder may be correlated with Mandai Kushtha, a type ofMahakushtha described by Charaka. In the present case report, a 31years old female presented with history of scaly pink patches on elbow, forehand, knee, lower limb, back and abdomen. Patient complained of itching and pin pointed bleeding points (Aupitz’s sign). As Ayurveda advocates Shodhan (purificatory) and Shamana (palliative) measures for its prevention as well as curative aspect, the patient was treated by Vamana as Shodhana chikitsa and internal ayurvedic medication. (Abhyantar/Shamana chikitsa).

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Prakriti is the profile or unique psychosomatic temperament of an individual, encompassing his or her physical, functional and behavioral characteristics. In Indian system of healthcare, three Doshas, namely, Vata, Pitta, and Kapha, are the basic mutually reciprocal mechanisms that are responsible for the maintenance of homeostasis in human beings. First of all the mostly accepted theory of prakriti is based on tridosha.Ayurveda classifies entire human population into seven constitutional types (Prakriti), based on the dominance of any single or a combination of two or three Doshas. Purusha or the body is considered to be a combination of various components like Dosha, Dhatu, Indriya, Manas, Buddhi and Atma. Like genetic coding, every individual has a different combination and is therefore a distinct entity. Dietary preferences, behavioral patterns, job options, performance abilities are all strikingly different between any two individuals. Knowing one’s Prakriti holds the key to health, liberation, and ultimately, self-realization.

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“Rasanimittameva Sthoulyam Karshyam Cha “ is the statement of the Ayurveda, i.e. either the obesity or emaciation is by “Rasa” ( nutritive material). Obesity is observed all over globe as metabolic disorder either with central or local with visceral and visible obesity classification. Indian population is with more visible obesity accumulated fats in buttocks, groin and abdomen. Many traditional and conservative management are in practice to reduce the visible and vascular fats. Vibration therapy a conventional massage with machine under dry conditions is capable of reducing the visible and visceral fats. Regularized timely meals are advised and instructed to avoid any food in between. To facilitate the bowel moments (Koshta-Suddhi), 5gms of Gandharwa Haritakichurna is advised at 5 AM. The results express statistically significant with a mean difference of 4.4. Kg weight, 2.54 BMI reductions, 12.5 cms in waist and 6.5 Cms is hip with a waist hip ratio difference of 0.074. On the other hand it shows significant reduction in mean lipid profile also. The serum cholesterol is reduced in 65.6, LDL with 18.8 and glycerides with 13.4 units. The overall feelings of the attended patients are feeling lightness in 3-6 days, reduction of 1 to 2 Kg in 8 to 10 days. The all measures are stable at the follow up undertaken after 30 days of treatment execution completion.

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Symphorema polyandrum Wight. seeds are reported for its use in the management of snake bite, scorpion stings and associated skin ailments. The alcoholic extracts of its seed was screened for in vitro antimicrobial activity following agar diffusion method and compared with Gentamycin, Cefpodoxime, Streptomycin as standard antibacterial and Amphotericin B, Fluconazole and Clotrimazole as standard antifungal agents. For antibacterial assay B. subtilis, S. aureus, S. epidermidis, E. coli, K. pneumonia , S. typhi and for antifungal activity on A. flavus and C. albicans as test organisms in different concentrations (25μg/ml, 50μg/ml, 100μg/ml and 250μg/ml), were evaluated following standard procedures. It was observed that the seed extract is effective against all six bacteria and two fungal strains, when compared to standard drugs. The zone of inhibition for antibacterial activity of the test drug, against 6 strains of bacterias was found between 11 to 15 mm and 12 to 17 mm for two fungal strains.

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Obesity vis-à-vis Sthoulya is a metabolic disease with accumulation of fat in body dependent parts and circulation as serum cholesterol (Sarakta Medas). Obesity is a leading reason for people death becomes an epidemic in 21^st century, where in 75% Indian women in the cities are apple shaped, while 58% of men are as so. Present study evaluate the effect of Bruhat Panchamuladi Yoga (Oral and Yogavasti) in obesity with reference to weight, BMI and Serum cholesterol. Study is undertaken in 2 groups with study design as Simple random sampling technique clinical trial. Internally 1500mg/ 24hrs in distributed doses of TDS or 25mg/kg body weight /24hrs of Bruhat Panchamuladi ghanavati and Bruhat Panchamuladi yoga Yoga vasti as per classical text for 8 days. The mean reduction is shown in Ayurveda subjective parameters and the W.H. Ratio has shown significance than any other with 8.04 % of mean reduction against Weight reduction is of only 4.76% and B.M.I. with 4.68% of mean is not significant.

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Constant research in Ayurveda is essential to update and upgrade the existing knowledge with currentresearch trends. Several problems have been encountered in Ayurvedic research, hence it is essential forresearches to know these problems and find ways to resolve it. The major issues inAyurvedic research includequality control, standardisation, lack of standard protocol, and lack of publication awareness. Raw drugstandardisation can be achieved by taxonomy and pharmacognostic tools like fingerprinting techniques, GMP and GAP could be few measures for standardisation of manufacturing process and the end product. The experimental and clinical models chosen should be designed in accordance with the principles of Ayurveda. Interdisciplinary research can bring much needed development in the field ofAyurveda.

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Intelligence is a vital essentiality in day today life in its purest and enriched form, especially in children who have to build up their life in an appropriate manner. Individuals with high level of intellectual power are inevitable for the current competitive era and factors influencing them are numerous as they embark to relate with one’s life from birth till death. Biological factor has a significant impact in influencing the intelligence. Few references in this regard are also found in Ayurveda which indicate their importance in influencing both the physical as well as the psychological health of an individual. The review focuses on to amplify these concepts and to emphasize upon the need to understand them by which the needy are dealt effectively. Upon analyzing the role of biological factors it can be concluded that these factors indeed affect the intelligence of School going children both positively and negatively.

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