Vatavyadhi (diseases caused by vitiation of Vata) are one of the most prevailing health problems and Gridhrasi (disease in which person walk like Vulture) is one among them. It is one of the painful conditions, where pain from the Sphik (Lumbar region) is radiates up to the Pada (Foot) through the posterior aspect of Kati (back), Prusta (thoracic region), Janu (knee) and Jangha (calf region) region. Gridharasi can be correlated with Sciatica based on symptoms. Basti (enema) is considered as an Ardhachikitsa (Half line of treatment) in Ayurveda treatment modalities; in present study Matra Basti is selected. Vajigandhadi Taila mentioned by Yogratnakara was used for the Basti karma which contains Erandataila (oil extracted from Ricinus communis), Ashwagandha (Withania somnífera), Bala (Sida CordifoliaI, Bilva (AegleMarmelos) and Dashmoola which exert Vatahara and Vedanasthapaka (pain killer) action. Ashwgandha acts as Rasayana (rejuvenator) and also causes defensive action on pain. Tila tail (sesame oil) when processed with drugs (Murchita Tila Taila) acts as Sarvarogapaham (Useful in all diseases). 30 patients of Gridhrasi were randomly divided in to two groups. In Group A, patients received nine days treatment of Vajigandhadi Taila Matra Basti while in Group B, patients were treated with Moorchita Tila Taila Matra Basti for nine days. In present study both groups showed statistically significant result in subjective parameters like Ruk (Pain), Toda (Pricking Sensation), Stambha (Stiffness), Spandana (Muscle Twitcing/Fasciculation ) as P < 0.0001 and objective parameters Straight Leg Raising test and Bragards Test P< 0.001 except Knee Jerk and Ankle Jerk as p=1. Group A(Vajigandhadi Taila Matrabasti) clinically showed slightly better response than group B (Tila Taila Matra basti) without much statistical significance

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Ikshu Mool (root of Saccharum officinarum Linn.) is one of the easily available medicine mentioned as diuretic in Ayurvedic literature. Pharmacognostic and phytochemical studies of Ikshu Mool has not been done yet, hence this study was undertaken to find out pharmacognostic nature and phytoconstitute of Ikshu Mool. Phytochemical study showed presence of steroids, alkaloids, reducing sugar, absence of proteins, monosaccharides and pentose sugar in both alcohol and water-soluble extracts. Hexose sugar, phenolic compounds and tanines were found only in alcohol soluble extractives.In HPTLC the ingredients separated in aqueous extract were more in number than alcohol soluble extract because of high extractive value in water. Pharcognostic study showed various structures in Ikshu root such as epidermis hypodermal layer, epidermal cells, vascular bundles, metaxylem elements, protoxylem elements, fibres etc. Analytical study showed moisture content (11.63%), total ash (9.67%), acid soluble ash (7.58%) & insoluble ash (2.09%), water soluble (6.88%) & insoluble ash (2.79%),Sulphated Ash value(7.58% ) within API standards which shows standard quality of the drug. The aqueous & alcohol extractive values were 7.08%, 4.215%, respectively.

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Hypothyroidism is a condition in which the body lacks sufficient Thyroid hormone. Thyroid hormone plays a vital role in physiology and metabolism, chief complaint of patients are weight gain, fatigue, weakness, cold intolerance and constipation. In present study, the hypothyroid case in post natal period has been successfully treated with an Ayurvedic concept of Shleshma (Kapha Dosha), Medohar (removal of fat), Aamdoshahar (removal of toxins) and Dhatuvagni Vardhaka (increase cell metabolism) formulation. Weight and Thyroid profile were important tools for assessment in this study. Two months treatment showed marked difference in TSH and weight reduced from 55.95 μIU/dl to19.42 μIU/dl and from 64 kg to 60kg respectively. Combination of Kanchanar Guggulu and Aarogyavardhini Vati as Ayurvedic formulations, found highly significant in this hypothyroid case. Patient was completely treated by Ayurvedic medicines only, under strict supervision.

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Ayurveda an oldest science which deals with health, diseases, and their management by using herbal, mineral, and animal originated drugs. Rasashastra, a branch of Ayurveda specially deals with use of various minerals and metal along with the procedures required to transform them into therapeutically fit medicines. In Ayurveda there are three types of medicine, Asuri (therapy involving various hymens and rituals), Daiwi (divine therapeutics) andManavi (medicinal therapy). Rasaushadi (herbo- mineral and herbo-metallic medicines) comes under Daiwichikitsa. Rasaushadi are easy for administration, tasteless and required in less dose. Amlapittavyadhi (hyperacidity) explained mainly by Kashyapa while other Achyarya included this disease under Grahiniroga (duodenal disorders). Many Rasaushadhis are indicated for the management of Amlapitta. Almost 15 herbo-metallic formulations are mentioned in Amlapitta chikitsa in Bhaishajyaratnavali. Here this article aims to review some of the important Rasaushadhis used in Amlapitta chikitsa (treatment of hyperacidity) mentioned in Bhaishajyaratnavali. Research data is unavailable on all 15 herbomineral formulations mentioned in Bhaishajyaratnavali for treatment of Amlapitta. Formulation such as Bhaskaramruta abhrakam, Paniyabhaktagutika, Paniyabhaktavatika, Panchanangutika, Shudhavati gutika and Sitamanduram are not available in market and Leelavilasrasa, Amlapittantakloha, Sarvatobhadraloham and Trifalamanduram are available in market and claimed to have Amlapittahar action. However, there is lack of research works on these available formulations. In most of formulations honey, cow milk and Kanji (sour gruel) are used as Anupan (vehicle).

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Srotas is a structural and functional unit of the body through which substances flow from one part to another. Each Srotas is said to associate with two organs which are termed as Srotomula. Srotomula is the most vital part of the Srotas just like the root of the tree. In classics neither the detail description about Srotomula is available nor the reason mentioned for considering particular organs as the Srotomula. Hence the present study was undertaken with the aim to assess and evaluate the relation between Srotas and its Mula. Also it is essential to compare the views of both Charaka and Sushruta regarding Srotomula. For present study relevant information regarding Srotas and its respective Dhatu from Samhitas, various texts, articles etc was compiled and interpreted. After analyzing all the conceptual material it was found that Srotomula could be considered as either the originating place, storage place, controlling place, conduction place, terminating end or the site of manifestation etc. After comparing the views of both Acharyas it was found that Charaka has narrated the concept from physiological point of view whereas Sushruta has given more emphasis on the anatomical aspect of Srotomula.

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Snehapana is internal administration of Sneha (medicated or non- medicated lipid substances) with a definite therapeutic aim. Apart from nutritive value, Sneha gains importance even in therapeutic application especially in Ayurveda. Present work highlights the findings of an observational study in sixty children who underwent Snehapana. Arohana Snehapana in children needs to be addressed on background of acceptance, smell, quantity, taste etc along with the diet schedule to be followed. Vicharanasneha (administration of Sneha either with food orally or other routes) can be adapted in administration of Shamana (Palliative), Brihmana (Nourishing) and Shodhananga Sneha (just prior to cleansing). Aversion to Sneha is major challenge to manage during administration in children. There is need to explore alternative route to improve the acceptance in children. Shodhana (detoxification therapy) following Snehapana reported to give excellent results in management of chronic allergy, respiratory and skin disorders

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Most of the Ayurvedic medicines are quite costly as compare to modern medicine. This is due to scarcity of raw drugs and high processing cost, which leads to difficulty for pharmaceutical company to control the cost of finish product. Conventional decoction techniques are quite time and fuel consuming hence Ayurved pharmaceutical industries are looking for cost effective techniques that do not compromise with the quality of finish product. Hence there is need to adapt new techniques which are easy, requires less raw drugs and can give quality assurance in terms of active principles. Ultrasonic extraction technique is one of the modern technologies, which has benefits such as fast extraction of active constituents, low costly, and environment friendly and selective extraction of valuable compounds. Due to its acoustic cavitations phenomenon it saves thermo sensitive constituents of crude drugs. Its application may be beneficial for Ayurved pharmacy industries, which are struggling for cost factor of finish products.

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Hyperglycemia is major representative symptom of diabetes. Increasing global incidence of diabetes is serious issue and large numbers of researches are undergoing to find promising cure of this chronic disease. In Ayurveda, Naga Bhasma (incinerated lead) is mainly indicated in treatment of Prameha (diabetes) as one of the potent metallic formulations. There are few published research works in which antidiabetic effect of Naga Bhasma has been studied. However according to classical texts Bhasma prepared by using mercury are considered as superior than those prepared by using herbal media. Comparative antihyperglycemic study of Naga Bhasma prepared by using mercury (NBP) and by using Vasa (Adhatoda vasica Niss) as herbal media (NBH) is not available. Hence in present study an attempt has been made to explore antihyperglycemic effect of Naga Bhasma prepared by two different methods in Wistar strain albino mice. Both drug reduced the sugar level at 90 and 120 minutes at almost similar level as observed at initial reading and the effects were significant in comparison to control group. Experimental study shows that both samples of Naga Bhasma have no hypoglycemic action but possess moderate anti- hyperglycemic effect after one hour and significant anti-hyperglycemic effect compared to initial blood sugar level.

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Presents work deals with description of anatomical variation in the left vertebral artery originating from the arch of aorta. This variation was in one of the cadaver in the department of Sharir Rachana at SDM College of Ayurveda Hassan, Karnataka (India). During routine dissection of a female cadaver of aged 60 years, in the superior mediastinum and rootof the neck, atypical origin of the left vertebral artery was observed. Atypical origin compared to the typical origin of the left vertebral artery in the anatomical literature. Findings compared with different possible variations of the origin of the left vertebral artery reported in the literature

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