Urethral strictures arise from various causes and can result in a range of manifestations, from an asymptomatic presentation to severe discomfort secondary to urinary retention. Establishing effective drainage of the urinary bladder can be challenging. Patients with urethral stricture disease appeared to have a high rate of urinary tract infection (41%) and incontinence (11%). Stricture disease may occur anywhere from the bladder to the tip of the penis. According to Ayurveda it can be correlated to Mutrasanga. In this case report patient was a diagnosed case of meatal stenosis with proximal bulbar urethral stricture with balanitis xerotica obliterans and underwent surgery before one year. Patient come with complaint of re-occurrence of symptoms and this time retrograde urethrogram shows bulbar urethral stricture with mild cystitis – 5.2mm, pre void – 400ml, post void - nil Case was managed by Uttarabasti and complaints were reduced up to 80%.

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Research over the past four decades has consistently shown the burden of Dyslipidemia to be very high in terms of morbidity, mortality and medical costs. The World Health Organisation estimates that Dyslipidemia is associated with more than half of global cases of IHD and more than 4 million deaths per year. In Ayurveda Dyslipidemia can be compared to Medoroga (Lipid disorders) which is Santarpanotha Vyadhi (Disease due to over nutrition) and Vamana karma (Therapeutic emesis) is the preferred line of management. Vamanakarma is the best therapy for the elimination of Kapha Dosha and related morbid factors. As Medodhatu (fatty tissues) is one of the substance belonging to the category of Kapha, in this trial Vamana Karma is selected for the treatment of Dyslipidemia. Kutaja Beeja churna (powdered seeds of Holarrena antidysentrica) is selected for Vamana karma which is indicated mainly in Kapha diseases, Hridroga (Heart diseases) and similar condition arising out of excessive Kapha and Meda. Therefore it has been selected for Vamana Karma in 15 patients. After Vamana Karma, in the follow-up Lekhaneeya Ghana Vati was given for 45 days. The results of the trial were highly significant in reducing lipid levels.

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A 22 year old female presented with burning maturation, throbbing pain in lower genital region associated with lower backache in sacral region, this pain aggravated after coital action and occasional vaginal discharge since last 2 years. No significant illness on her past life and her family history was also normal. Her vaginal speculum examination shows that she was suffering from cervicitis and urethritis that lead to diagnosis as UTI as per modern medicine and Pittaj Yonivyapada (Vaginal disorder due to vitiation of Pitta Dosha) as per Ayurvedic point of view. All investigations were done, CBC was found within normal limit. Routine and microscopic urine examination revealed plenty of pus cell and occasional red blood cells. Used drug in treatment was Triphala Kwatha (Decoction of Triphala) for Yonidhavana (cleaning of vagina) i.e. Yoniprakshalana (cleaning of vagina) for 7 days in three successive menstrual cycles considering Sthanik Dosha- Dushti (Local infection). Assessment criteria were burning maturation, pain in lower genital region, lower backache and vaginal discharge. Result of this case study found that significant result in all assessment criteria. Therefore it is concluded that Yonidhavana by Triphala Kwatha is an effective therapy in recurrent urinary tract infection.

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Pharmaceutical standardization is the first step towards preparation of safe and effective medicines. Trinetra Rasa, an Ayurvedic herbo-mineral preparation is one of formulation which is indicated in life threatening condition such as cardiovascular diseases. Hence an attempt has been made for pharmaceutical standardization of Trinetra Rasa. This formulation is mentioned in Bhaishajya Ratnavali. Extraction of mercury from cinnabar, purification of sulphur, preparation of mercurus sulphide (Kajjali), purification of Abhraka, Dhanyabrikarna and incineration of Abhraka are the procedures required to be performed before preparation of Trinetra Rasa. 20 Puta were required for preparation of Abhraka bhasma. Trinetra Rasa can be prepared from Parada extracted from Hingula, Shuddha Gandhaka, Abhraka bhasma. Arjuna twak qwatha is needed for 21 Bhavana. Analytical profile of Trinetra rasa indicates that it is highly complex structure and predominantly oxide form with Hg-0.31%, S-3.27%, Fe-1.59%, O- 31.53%, C-49.94%, Al-4.60%, Si-5.81%,Mg-0.55%,K-2.41%.

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“Netra”, the Eyes hold special status among the all sense organs. Tremendous advancements that have come across in ophthalmic care from ages until recent era is a boon for the Ayurvedic Ophthalmology. The word Kriyakalpa comprises with two words Kriya and Kalpa. Kriya means therapeutic procedures used to cure disease and Kalpa means practicable, possible manner of acting, prescribed rule. Kriyakalpa means specific formulation used for therapy in Ayurvedic Ophthalmology. It includes selection of specific procedure, preparation of special drug form and proper application to the eyes. One such Ayurvedic ocular therapeutic is Kriyakalpa. Ayurvedic ocular therapeutics “Kriyakalpa” includes specific formulations and procedures of Ayurvedic Ophthalmology. Netra Tarpana(Eye gladdening) is one among five Kriyakalpa procedures. Netra Tarpana is most prominent and widely recommended Kriyakalpa in 80% of ocular ailments. In this review an attempt is made to understand the significance and scientific basis of Kriyakalpa and in specific Netra Tarpana through search engines. The ocular conditions like Dry Eye Syndrome, Computer Vision Syndrome, Myopia and other can be treated successfully with Netra Tarpana. Susruta has recommended Netra Tarpana in healthy individual as a eye gladdening and rejuvenation therapy. The results show that highest number (n=89 in Google scholar; n=5 in PMC) in two indexing areas shows the importance and popularity of NetraTarpana in ophthalmic care.

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Balachaturbhadra Churna is drug of choice in many paediatric conditions such as respiratory disorders, fever, diarrhoea and vomiting. This formulation has bitter taste, lesser shelf life and children are reluctant to consume this Churna. Modification of this powder dosage form into Sugar syrup will not only enhance the palatability and shelf life but also efficacy of this formulation. Balachaturbhadra Churna has been done to convert it in to Tablet and Avaleha form by some researchers. In current study an attempt has been made for dosage modification and pharmaceutical standardization of Balachaturbhadra syrup. Ingredients for preparation of Balachaturbhadra syrup were collected from Dattatrey Ayurved Rasashala and standard method adopted for preparation of syrup. Formulation was analyzed by employing various analytical parameters like organoleptic characteristics, Physico-chemical parameters, microbial growth and HPLC. Average time required for preparation of Balachaturbhadra syrup was 1.12 hrs, after adding sugar to the Kwatha (decoction). It took average 1hr and 05min to attain one thread consistency. Average specific gravity, refractive index and average reducing sugar of prepared Balachaturbhadra syrup are 1.66 gm/ml, 1.51 and 9.78% respectively which is within limit of committee standard. HPLC analysis detected flavonoids which have distinct flavone ring structures.

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Vidarbha, is extreme Northern Maharashtra situated in central India. The rainfall and the Government nurture the small strips of Forestry that consists of many herbs used in Ayurveda. Apart from standard textual referential Govt. of India listed herbs, many folklore usages found from the local users. The Chincholi (East) Beat in Garpeeth Dhamakund is approximately, 350.94 hectares in area. Fifteen Ayurvedic surveyors, two Botanists along with four Forest officials conducted a survey in the Garpit Strip for 12 hours. In the survey, medicinal use of the specific species are well identified are 51. These 51 are naturally grown herbs in its habitat. Out of that 28 ethno-medicinal plants documented in this paper. Apart from forest nursery, contain 67 varieties of plants that are cultivated. Out of 51 identified in this province, 16 are abundant and 12 are scanty and rare.

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Avascular necrosis is a disease in which cellular death of bone component occurs due to interruption of the blood supply. Necrosis causes due to arterial occlusion and lack or insufficient blood supply, the bone tissue dies and there occurs collapsing of that bony segment. The disease found in age of 35 to 45 yrs. Head of femur is one of the classical site of Avascular necrosis. Avascular necrosis is a progressive disorder with surgical intervention as the prime choice. If left untreated, the disease progresses, there occurs collapsing of necrotic bony segment. All the treatment procedures are cost worthy and prognosis is very poor. In present study a female patient of 38 yrs old having signs and symptoms of Avascular necrosis and X-ray of right hip showing Avascular necrosis of femoral head and palliative (Kaishor Guggulu, Amalaki Rasayana, Chanadraprabha vati, Ashwagandha powder, cold decoction of Hemidismus indicus & Rubia cordifolia along with Panchakarma treatment such as local massage steam with Panchtikta kshirbasti & Pindasweda additional with Tub bath (Avgaha sweda) was given for 6 weeks. Significant result was observed and there was improvement in cardinal sign & symptoms of Avascular necrosis of femoral head. It also provides noteworthy results in improving range of movements and pain intensity. Overall result of the therapy was found to be effective with no pain and limping while walking with free movements of joints. Recovery in Right hip joint was 100% whereas limping and walking difficulty were reduced up to 90 % & 95 % respectively.

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Obesity is not only medical risk factor but also a serious social, psychological and economic problem. Average 2.3 million people die every year as a result of being obese and it became a threatening global crisis than hunger. Though modern system of medicine has its own therapeutic modalities in tackling obesity but is associated with certain adverse effects. In such scenario; suffering global population is enthusiastically looking towards effective natural remedies. Acharya Charaka has describedRuksha, Ushna and Tiksna Vasti in the management of Sthaulya (Obesity). Many treatment modalities are also available in Ayurveda for obesity, but none is as effective as that of Lekhana Vasti. A few studies were reviewed and compiled to evaluate the clinical efficacy of Lekhana Vasti in the management of Obesity. Present attempt is to evaluate the actual efficacy of Lekhana Vasti in the management of Obesity through works done at IPGT and RA, Gujarat Ayurveda University, Jamnagar. Significant results were found with Lekhana Vasti that provided better results in reducing weight and anthropometric measurements as compared to other treatment.

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Medicinal plants are the most important source of life saving drugs for the majority of the world's population. The world health organisation gives the estimate that up to 80% of the world's population relies on medicinal plants. The demand for medicinal plants is rising in the industrialized world. Heavy demand of such plants has threatened some species and put them to the level of extinction. 70 percent of plant collections involve destructive harvesting. Such unscrupulous collection of these plants by local unskilled people endangers the existence of several medicinal plants. To overcome the problems of over exploitation of natural resources, emphasis should be given to encourage commercial cultivation using modern biotechnological tools. The biotechnological tools are important to select, multiply and conserve the critical genotypes of medicinal plants. In this paper various biotechnological tools used and the merits and demerits of genetically modified varieties of medicinal plants will be discussed.

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