Tuberculosis remains the major health problem not only in India but also in world. According to World Health Organization, one third of global population is suffering from tuberculosis. In India, genital tract tuberculosis is defined as an important cause of infertility. In various reports, the prevalence of genital TB has been reported from less than 1% to over than 20% in different countries. Reports indicate that this condition affects about 10 to 20 % of couples of the reproductive age around the world. Add-on therapy means any treatment given to bolster or enhance the effectiveness of a previous one, especially when the first treatment proved not to be fully effective. It is now times to offer new add on therapies to anti-tubercular drugs like effective formulations of Ayurveda in the management of Genital Tuberculosis. An Ayurvedic formulation - Jivantyadi Ghrita of Charak Samhita in female genital tuberculosis is scrutinized in this study.

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Hypothyroidism is one of the most common functional disorders of thyroid gland and is a very commonly encountered problem in clinical practice. The prevalence of hypothyroidism in the developed world is about 4-5%and the prevalence of subclinical hypothyroidism in the developed world is about 4-15%. Hypothyroidism refers to any state that results in a deficiency of thyroid hormone, including hypothalamic or pituitary disease and generalized tissue resistance to thyroid hormone, and disorders that affect the thyroid gland directly. Many of the symptoms of Hypothyroidism can be correlated with Lakshanas (Symptoms) of Bahudosha (excessive vitiated Dosha) mentioned in Ayurveda. Excessive accumulation of the Dosha in the body is called Bahudoshavastha. This condition is aptly suitable for Samshodana/Panchakarma (detoxification), in support to the statement, certain research works done on hypothyroidism were analysed, and it was observed that Samshodhana had shown better results on the symptoms of the disease. Few researches conducted to find out the efficacy of Ayurveda treatments particularly Samshodhana treatment like Vamana Karma (Therapeutic emesis) and use of Agnideepana (Carminative) drugs and Guggulu preparation. In these studies it has been correlated with Dhatvagni Mandhya, Kaphavruta Vata etc. In clinical practice it was observed that many of the symptoms of Bahu Dosha closely resembles with that of Complains of the patients suffering with Hypothyroidism. Hence the present study was done with the aim to understand the disease and its Ayurvedic correlation along with outcome of certain research works in support to the concept has been elaborated.

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Menopause is defined as a stage when there is decrease in hormone production by the ovaries. In India, a total of 130 million women are expected to live beyond menopause by 2015. Long term use of modern medication is associated with many adverse effects like- increase the risk of deep vein thrombosis due to Hormone Replacement Therapy and pulmonary embolism, flatulence, constipation and bloating from use of calcium, weakness, fatigue, sleepiness, headache, loss of appetite, dry mouth, metallic taste, nausea, vomiting from use of vitamin D, gastric irritation and pain in lower extremity and selective estrogen receptor modulators and other estrogen analogous increase the risk of endometrial cancer. In Ayurveda it may be correlated with Rajonivriti Janya Lakshana (Post-menopausal Sign & symptoms). Vitiated stage of Vayu may be the case of Rajonivritti (Post-menopausal stage). Taila (Oil) is first line of treatment for Vata Vyadhi further Brimhana Sneha is best in Vruddhavastha (Old age). Rasayana and Balya drugs like Amrita (Tinospora Cardifolia), Asthishrinkhala (Cissus quadrangularis), Shatavari (Asparagus racemosus), Shunthi (Zingiber officinails), Methica (Trigonellafoenum graecum) and Madhuyasthi (Glycyrrhiza glabra) are used as a Rasayana Ghanavati (Kalpita Yoga). The result has been analyzed statistically. Result was statistically very significant (P 0.001s) in Sandhi Shoola (Joint pain) andKatishoola (Backache), significant (P <0.01) inRaukshaya (Dryness of skin), Bhrama (Vertigo), Aswapna (Loss of sleep),#rit Dravatva (Palpitation) and Shirah Shoola (Headache). Brimhana-Sneha and Rasayana Ghanavati were found to be highly effective in Post-menopausal syndrome which was statistically significant (P <0.01).

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Amavata (Rheumatoid Arthritis) is one of the commonly affected lifestyle and degenerative disease which was first described as an independent disease inMadhava nidhana (Ayurvedic text). It is a disease of Madhyama Roga Marga (Middle disease pathway) as it effects Sandhis (joints) andHridayaMarma (Heart). RAis a chronic degenerative disease of the connective tissue mainly involving the joints. Swelling and pain in multiple joints are the main features of Amavata. RheumatoidArthritis is a Auto immune disease that causes inflammation of the joints affecting mostly the middle aged females than in males. RA is typically treated with NSAIDS, Corticosteroids and immune-suppressive drugs which unfortunately causes hepato-toxicity, renal damage on prolonged use. So in the present study Asitakadi Churna (Ayurvedic powder medicine) for Amavata was selected. It acts as Amapachana (Biotoxin neutralizing), Agnideepana (Enzyme activating), Vatakaphahara (Balancing Vata- Kapha physical Constitution), Rechana (Purgation), Vedana stapana (Analgesic), Shoolahara (Pain reducing) Shotahara (Anti-inflammatory) andRasayana (Immuo-enhancer).

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Infertility is emerging as one of the serious problems in the present world. The contemporary life style, socio-economic plights, environmental pollution, mental stress and strain have greatly affected the normal sexual behavior and fertility. Main purpose of Vrishya (aphrodisiac) is to become lovable among women by providing sexual contentment, procreation, to get a strong, better and genetically good progeny and enhancement and maintenance of body strength. Vrishya dravyas are mainly classified as Shukrajanaka, Shukrapravartaka, Shukrajanakapravartaka, Shukrastambhaka and Uttejaka. Vrishya dravya acts at psychic as well as somatic level. Vrishya dravyas are sweet, unctuous, promoters of life and weight, heavy to digest and produce excitement. Vrishya dravyas can be a ray of hope to the patients of Infertility in case of Oligospermia, azoospermia, erectile dysfunction, early ejaculation apart from diet and life style management & on the contrarily helpful for the development of better progeny.

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“Standardization” expression is used to describe all measures, which are taken during the manufacturing process and quality control leading to a reproducible quality. Standardization ofAyurvedic drugs is a need of the hour in the field of Pharmacy. In ClassicalAyurvedic texts the parameters given are mostly subjective. Hence there is a need to set some objective parameters through pharmaceutical study and Analytical study. Rajapravartini Vati (Tablets) is prescribed for the treatment of scanty bleeding and amenorrhea. Dosage form plays important role in delivery and proper action of particular. In this research paper, an attempt has been made to develop pharmaceutical and analytical standards for Rajapravartini Vati. Three samples were prepared and evaluated on the basis of ayurvedic as well as modern parameters. All three samples shows identical parameters and shows no significant difference. The set parameters were found to be sufficient to evaluate the Rajapravartini Vati and can be used as reference standards for the quality control/quality assurance in future.

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This study is carried out with the aim to evaluate Agnidipana (loss of ap. etite) effect of Haritakadi vati which comprises Haritaki (Terminalia chebula), Sunthi (Zingiber officinalis), Saindav (rock salt) in equal proportion. A randomized open clinical trial on 60 patients of Agnimandya has been screened on the basis of clinical findings and the patients were allocated to three groups consisting 20 in each group. Group I were placebo group, Group II received Luke warm water group and Group III received Haritakadi vati with luke warm water for 60 days Special scoring pattern was done for the assessment In placebo control group18 (90%) no relief and mild relief 2(10%) while in luke warm water group II 18(90%) patient got moderate relief and 2(10%) got complete relief and group III Haritakadi vati with luke warm water 20 (100%) patients got complete relief. So to prevent further disease formation and to treat Agnimandya; Haritakadi vati was found very useful.

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Abstract The herbal formulations are prepared by potentiating properties of drugs. It aids a physician to utilize formulations in various forms and techniques to fight the disease. But there are some demerits of these formulations such as large amount of dose, unpleasant palatability, less shelf life and difficulty in portability. Modification in the formulations without changing its efficacy is need of hour in today’s era for the feasibility, palatability, minimum dose, easy administration, increased bioavailability and better shelf life. Present study was planned to Pharmaceutical standardization of Triphala mouthwash. Triphala gandush mentioned in Bhaishajya ratnavali and indicated in diseases of oral cavity. This formulation is advised in kwatha form but it becomes inconvenient in terms of preparation, palatability and shelf life. hence it is converted into mouthwash Triphala Mouthwash. Pharmaceutical preparation and analytical study of Triphala Mouthwash was carried out at Dattatraya Ayurved Rasashala, Mahatma Gandhi Ayurveda Collage Hospital and Research center, Salod (H) Wardha, Maharashtra.The formulation was tasted for organoleptic parameters such as odour and colour, physico-chemical analysis and microbial specifications. Modified Triphala Mouthwash had dark brown color, astringent test with specific tannin smell,. Analytical standards for Triphala Mouthwash such as pH, refractive index and solid contents were 3.92,1.36 and 3.96% respectively. No microbial contamination found.

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The present case study on a patient of dyslipidemia was conducted to evaluate the effect of dietary herbs on the lipid level which helps to prevent cardio-vascular risk. Ayurvedic literature mentions uses of dietary ingredients in the form of medicines instead of therapeutic formulations, which proves beneficial as an adjuvant therapy in curing ailments and reducing the risk of major diseases. In the present context, four drugs in the form of Pippalyadi dietary herbs were taken. The above formulation was given to the patient who was diagnosed a high risk candidate of developing a cardio-vascular disease for about 2 months after meals twice a day. The objective criteria taken for assessment was weight in Kg, lipid profile, anthropometric measurements while subjective criteria for assessment was hunger, thirst, bowel habit etc. Results showed that there was a gradual decrease in the level of lipid along with decline of other symptoms. Changes were noticed in the following assessment criteria. BMI was reduced to 29.38 along with reduction in waist circumference by 4cm. Also, changes were observed in the total cholesterol, LDL and HDL levels. Intake of Pippalyadi dietary herbs in the form of micro-nutrients is quite effective in reducing the cholesterol/lipid levels and eventually preventing the risk of CVD.

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